One antidepressant shown to control weight during 2-year study

Bupropion (marketed as Wellbutrin) is the only antidepressant that tends to be linked to long-term modest weight loss, new research indicates. Previously, researchers linked depression to obesity–and most antidepressant medications to weight gain. The new study suggests that bupropion is the best initial choice of antidepressant for the vast majority of Americans who have depression and are overweight or obese.