Prediabetes: Fatty liver, visceral obesity, production and action of insulin modulate risk

Prediabetes is associated with increased risk of diabetes, cardiovascular disease, dementia and cancer. However, the disease risk considerably varies among subjects. Scientists have now summarized information from the literature and have provided novel data indicating that in future the determination of the 4 major phenotypes fatty liver, visceral obesity and impaired production and action of insulin may help to improve prediction and prevention of cardiometabolic risk in prediabetes.