Strategies to mimic fasting during chemotherapy enhance anticancer T cell activity in mice

Fasting is known to increase positive outcomes during cancer treatment, and now two independent studies in mice show that fasting, either through diet or drugs, during chemotherapy helps increase the presence of cancer-killing T cells. The research teams show that rodents that received caloric restriction mimetics alone or chemotherapy combined with a fasting-mimicking diet had smaller tumor masses over time than those that received only chemotherapy.