Standing up may unmask cognitive deficits in patients with Parkinson’s

This study shows that when patients with PD experience a drop in blood pressure upon standing up – a condition known as orthostatic hypotension (OH) – they exhibit significant cognitive deficits. These deficits reverse when the individual lies down and their blood pressure returns to normal. As a result, these findings are important as clinical providers might miss an important target for intervention when not considering OH as a contributor to cognitive impairment.