Antiviral protein linked to depressed mood in mice

Posted by on April 19, 2016 5:00 pm
Categories: health

The flu and other viral infections have long been known to cause mood changes, beyond the more familiar symptoms of fever and sore throat. A study in mice now reveals how the antiviral immune response alters brain activity. Upon infection, brain cells lining blood vessels produce a protein called CXCL10, which impairs neuronal firing in the hippocampus — a brain region important in learning, memory, and mood.

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