Long-noncoding RNA regulates repair of DNA breaks in triple-negative breast cancer cells

Posted by on April 28, 2016 9:32 pm
Categories: health

Using a clinically guided genetic screening approach, researchers identified a non-coding RNA that is overexpressed in triple-negative breast cancer cells and regulated by the tumor suppressor p53 and the activated cell surface protein, EGFR. This molecule enhances the repair of DNA breaks by serving as a scaffold that links two other proteins in the repair machinery.

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