Quieting cells’ low-oxygen alarm stops flare-ups in rare bone disorder

Posted by on May 2, 2016 5:14 pm
Categories: health

The cellular response to the lack of oxygen fans the flames of flare-ups in a rare bone disorder. In fibrodysplasia ossificans progressiva, a mutation triggers bone growth in muscles, which limits motion, breathing, and swallowing, among a host of progressive symptoms. The study identifies a therapeutic target for stopping the extra bone growth in FOP and other disorders.

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