Parkinson’s disease pathogenesis reduced in rat model by a cell-signaling inhibitor drug

Posted by on May 4, 2016 1:29 pm
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Categories: health

Researchers report the first documentation that suppressing a key cell-signaling pathway in a rat model of Parkinson’s disease reduces pathogenesis. Oral administration of AZD1480 — one of the JAK/STAT pathway inhibitors generally known as Jakinibs — lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson’s.

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