Nuclear DNA gets cut, activates immune system to attack cancer cells

Posted by on May 10, 2016 5:27 pm
Categories: health

The enzyme MUS81 cuts DNA in the nucleus of cancer cells, causing the cut DNA to move to the cytoplasm instead of becoming degraded. The out-of-place DNA triggers an immune response against cancer cells. Discovering this new means of enhancing anti-cancer immune responses could lead to more effective cancer therapies using a combination of a MUS81-stimulating drug and an immunotherapy.

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