New approaches to eradicate aggressive breast cancers

Posted by on May 12, 2016 12:45 pm
Categories: health

Medical researchers have identified fatty acid oxidation intermediates as being significantly upregulated in a MYC-driven model of TNBC. In the MYC-driven transgenic TNBC model and also MYC over-expressing TNBC PDX models, they found that inhibition of FAO decreased energy metabolism and blocked tumor growth, suggesting that FAO has a critical role for in vivo tumor activity.

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