Gut microbes’ metabolite dampens proliferation of intestinal stem cells

Posted by on June 2, 2016 5:24 pm
Categories: health

Intestinal stem cells are located in ‘pockets’ in the intestine to avoid contact with a prominent metabolite produced by beneficial microbes living in the gut, new research indicates. That metabolite — butyrate — restricts the proliferation of stem cells, potentially hampering the intestine from repairing itself after an injury or damage resulting from inflammatory bowel diseases such as Crohn’s and colitis, say scientists.

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