New qPAINT technology gives microscopes ‘super-vision’

Knowing the exact number of molecules located at specific junctures in cells can be a critical measure of health as well as disease. For example, abnormally high numbers of growth factor receptors on cells can be an indication of cancerous and precancerous states. Now, a simplified method known as qPAINT uses the blinking pattern of the light that marks each molecule, to find, count, and study individual molecules that are just a few nanometers apart.