Cross talk between hormone receptors has unexpected effects

Posted by on June 24, 2016 7:47 pm
Categories: health

Although the estrogen receptor is considered dominant in breast cancer, the progesterone receptor assumes control when both receptors are present and exposed to estrogens and progestins. Then, the progesterone receptor drives estrogen receptor activity. Treating tumor-bearing mice with an estrogen antagonist and a progestin antagonist caused rapid tumor regression, report scientists at the conclusion of their study.

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