Melanoma tumors use interferon-gamma mutations to fight immunotherapy

Posted by on September 22, 2016 4:54 pm
Categories: health

Melanoma tumors use genetic mutations in a prominent immune response pathway to resist the immunotherapy ipilimumab, researchers report. These findings open the door to testing an array of IFN-y genes prospectively as a predictor for response to ipilimumab and for exploring new combinations to defeat IFN-y-related resistance.

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