Crosstalk analysis of biological networks for improved pathway annotation
A new computer algorithm for analyzing gene function called BinoX has been developed by researchers. The method associates experimentally derived gene lists and known pathways. It does this in a new way, by employing a large gene network and determining if a gene list and a pathway has more network links than expected, using the binomial distribution. This is a significant advance over previous methods, and as a result BinoX yields substantially better accuracy.