Crosstalk analysis of biological networks for improved pathway annotation

Posted by on September 27, 2016 12:29 pm
Categories: health

A new computer algorithm for analyzing gene function called BinoX has been developed by researchers. The method associates experimentally derived gene lists and known pathways. It does this in a new way, by employing a large gene network and determining if a gene list and a pathway has more network links than expected, using the binomial distribution. This is a significant advance over previous methods, and as a result BinoX yields substantially better accuracy.

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