Fertility genes required for sperm stem cells

Posted by on September 27, 2016 5:40 pm
Categories: health

The underlying cause of male infertility is unknown for 30 percent of cases. In a pair of new studies, researchers have determined that the reproductive homeobox (RHOX) family of transcription factors — regulatory proteins that activate some genes and inactivate others — drive the development of stem cells in the testes in mice. The investigators also linked RHOX gene mutations to male infertility in humans.

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