Ki67 may help avoid sentinel lymph node biopsy in some patients

Breast cancer patients over 50 years old could be spared invasive procedures by use of stratification based on tumor size and molecular characteristics, including Ki67. The cell proliferation index Ki67 is significantly associated with lymph node metastases in patients aged over 50 years and with smaller tumors, which may help reduce the need for sentinel lymph node biopsies in some women, researchers report.