Improving longevity of functionally integrated stem cells in regenerative vision therapy

One of the challenges in developing stem cell therapies is ensuring that transplanted cells can survive long enough to work. Researchers report one of the first demonstrations of long-term vision restoration in blind mice by transplanting photoreceptors derived from human stem cells and blocking the immune response that causes transplanted cells to be rejected. The findings support a path to improving clinical applications in restoring human vision lost to degenerative eye diseases.