Function of an enigmatic synaptic protein defined

Communication is often mired in contradiction — also in the brain. Neuroscientists have now resolved one such contradiction. The role of Synaptotagmin 7 has been controversial: There was a contradiction between the function it seemed to have, and the characteristics of signal transmission observed. Now, for the first time, scientists defined its functional contribution at an inhibitory GABAergic synapse: it ensures the efficiency of high-frequency inhibitory synaptic transmission.