Chemical compound produces beneficial inflammation, remyelination that could help treat multiple sclerosis

Researchers report that indazole chloride, a synthetic compound that acts on one form of the body’s estrogen receptors, is able to remyelinate (add new myelin to) damaged axons and alter the body’s immune system — findings that could help treat multiple sclerosis. Drugs available to treat MS alter the immune system but do not induce repair of damaged axons.