‘Undruggable’ cancers slowed by targeting growth signals

Posted by on August 13, 2018 3:33 pm
Categories: health

As many as 50 percent of human cancer cases — across a wide variety of tissues — involve defects in a common cellular growth signaling pathway. These defects have so far defied most attempts to develop targeted therapies. Now researchers have identified a new strategy for potentially treating intractable cancers by decoupling the entire RAS/MAP Kinase (MAPK) signaling pathway from external growth signals.

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