Tiny Robots Carry Stem Cells Through a Mouse

Engineers have built microrobots to perform all sorts of tasks in the body, and can now add to that list another key skill: delivering stem cells. In a paper published today in Science Robotics, researchers describe propelling a magnetically-controlled, stem-cell-carrying bot through a live mouse. 

Under a rotating magnetic field, the microrobots moved with rolling and corkscrew-style locomotion. The researchers, led by Hongsoo Choi and his team at the Daegu Gyeongbuk Institute of Science & Technology (DGIST), in South Korea, also demonstrated their bot’s moves in slices of mouse brain, in blood vessels isolated from rat brains, and in a multi-organ-on-a chip. 

The invention provides an alternative way to deliver stem cells, which are increasingly important in medicine. Such cells can be coaxed into becoming nearly any kind of cell, making them great candidates for treating neurodegenerative disorders such as Alzheimer’s.